Journal of Multiple Sclerosis
ISSN - 2376-0389NLM - 101654564
Before being officially diagnosed with MS, patients usually experience a first neurologic event suggestive of MS, defined as Clinically Isolated Syndrome (CIS). It lasts for at least 24 hours with symptoms and signs indicating either a single lesion (monofocal) or more than one lesion (multifocal) within the central nervous system.1
