Raikan Buyukavcı, Fusun Sahin, Beril Dogu and Banu Kuran
Ankylosing Spondylitis (AS) is a chronic, systemic, and inflammatory rheumatic disease affecting primarily axial skeleton. In cases non-responsive to classical therapeutic approaches, tumor necrosis factor-α (TNF-α) antagonists have become new treatment alternatives. With anti-TNF drugs usage, rate of lymphoma development has increased especially in patients with rheumatoid arthritis. In this case-report, we report a patient with (AS) who presented with Hodgkin Lymphoma (HL) at the 3rd month of anti-TNF therapy. This complication should be remembered and close follow-up should be pursued in patients who are under immunosuppressive therapy with anti-TNF drugs, which were also used in the treatment of rheumatic diseases.
