Journal of Multiple Sclerosis

An Unusual Association of Demyelinating Disease, Chronic Kidney Disease and Heart Failure

Roshan Patel, Aaron Stern, Maritza Brown and Rui Chang

Multiple sclerosis (MS) and its variant, neuromyelitis optica (NMO) are autoimmune diseases of the central nervous system that typically cause progressively disabling symptoms involving the entire nervous system. These diseases have rarely been associated with de novo heart failure and only in the setting of bladder dysfunction have they been linked to renal failure. The medications used to treat them can have significant adverse effects on kidney and cardiovascular system. We present a case of a patient with concomitant cervical demyelinating disease and heart failure who was also found to be suffering from chronic kidney disease of unclear etiology.