Till now numerous anti-microbials are accessible, yet some pathogenic creatures are demonstrating protection from existing anti-infection agents. So it is required to scan new anti-infection agents for opposing pathogenic life forms. Actinomycetes are excellent asset for delivering optional metabolites that is anti-microbials; they are Streptomycin, Erythromycin, and Tetracycline. Actinomycetes are accessible in both marine and earthbound environment. From earthly biological system disengagement of new strain Actinomycetes is exceptionally troublesome contrasted and marine environment. Marine environment is a best asset for some strains of actinomycetes, since it is unexplored biological system having a great many various kinds of organisms. Upto 1% of marine actinomycetes were separated, yet at the same time we need to investigate more for finding new organisms. The majority of the disengaged marine microorganisms are from Streptomyces class (70%), marine growths (20%), Bacillus spp. (7%) and other microbes (1%-2%). 40 isolates are obtained from sample, among them 8 isolates are selected from primary screening for antibacterial activity. Out of 8, 6 isolates showed antimicrobial activity against 4 test organisms. 2 isolates showed activity in secondary screening. S2 isolate showed broad antibacterial activity.
