Luh Putu Febryana Larasanty, Zullies Ikawati, Abdul Gofir
Background and Objectives: Intracerebral hemorrhage (ICH) stroke is a type of stroke with the highest mortality rate, with only about 38% of patients who survived for the first year after stroke. Antihypertensive treatment and therapy for increased intracranial pressure is still the main therapy for reduce the mortality rate in ICH. The objective for this research is to study the effect of early antihypertensive treatment and therapy for increased intracranial pressure on life expectancy of patient with ICH stroke during hospitalization in Dr. Sardjito Hospital.
Methods : 165 patients with ICH stroke who meet the inclusion and exclusion criteria divided into 2 major group for case control study. There were 81 patients in case and 84 patients in control groups. Data collection conducted retrospectively through patient medical record.
Results: There were 8 (9,88%) patients in case group and 19 (22,63%) patients in control group which didn’t get early antihypertensive therapy. Furosemide, nimodipine and valsartan is the most commonly used antihypertensive for ICH patients during hospitalization. Odds ratio for early antihypertensive therapy is 2,67 (95% CI 1,09 – 6,50; P 0,027). Patients which didn’t get therapy for increased intracranial pressure as much as 35 (43,21%) patient in case group and 36 (42,86%) patient in control group. Mannitol is one and the only agent used to treat increased intracranial pressure for ICH patient during hospitalization. Odds ratio for used of mannitol is 0,986 (95% CI 0,532 – 1,826; P 0,371).
Conclusions : Early use of antihypertensive therapy may increase life expectancy of ICH stroke patient during hospitalization. The relationship between the use of increased intracranial pressure therapy mannitol in ICH stroke patient during hospitalization and life expectancy of patients has not been established clearly.
