Alzheimer's Disease (AD) related mental disability and dementia have been connected to an assortment of hereditary, ecological, and way of life factors. While exploring precaution or ameliorative intercessions focused on dementia and its preclinical stages, an assortment of possibly modifiable gamble factors ought to be considered. This study investigated the connection between two such possibly modifiable gamble factors Bone Mineral Thickness (BMD) and body piece and mental impedance. For this longitudinal review, 164 patients were selected, who were tried intellectually and clinically at benchmark and after three years. Their ages went from 34 to 87. Double Energy X-Beam Absorptiometry (DXA) was performed around the same time as the mental appraisal, and blood tests were taken for Apolipoprotein E (APOE) genotyping. We found through various leveled relapse examination that BMD and lean, not entirely settled by DXA, were significant indicators of roundabout memory. Premorbid intelligence level, APOE status, age, and orientation were considered. Especially, BMD and lean mass were significantly related with Rundown A gaining from the California Verbal Learning Test at both the gauge and follow-up evaluations. Our outcomes show a significant connection between BMD, lean weight, and wordy semantic learning.