Sakshi Bisht
T-cell responses play a crucial role in the adaptive immune system, mediating targeted defenses against pathogens, tumors, and other abnormal cells. This article provides an in-depth exploration of T-cell biology, focusing on the mechanisms underlying T-cell activation, differentiation, and function. It examines the diverse roles of T-cell subsets, including CD4+ helper T cells, CD8+ cytotoxic T cells, and regulatory T cells, in orchestrating immune responses. The review also addresses the impact of T-cell responses on various diseases and discusses emerging therapeutic strategies, including immunotherapy and vaccines, that leverage T-cell functions. By integrating recent advancements in T-cell research and clinical applications, this article aims to present a comprehensive understanding of T-cell responses and their significance in health and disease.