Diana Laila Ramatillah, Syed Wasif Gillani, Muslim Suardi
Introdcction: Various treatments performed for this disease such as surgery, chemotherapy, radiotherapy, hormone therapy and immunomodulators. Before treatment is done well or let the patient's condition as stable as it was the chemotherapy. Than chemotherapeutic drugs that are excreted through the kidneys so as to affect kidney function. Methotrexate, cisplatin, 5 fluorouracil and cyclophosphamide is a cytotoxic drug that is often present in the chemotherapy protocol.
Objectives: This paper reports how the effect of cytotoxic drugs (MTX, cisplatin, 5 FU and cyclophosphamide to the patient as well as creatinine clearance relationship with creatinine clearance of urea cancer patient.
Methology: The research was conducted using longitudinal study design and methods of a prospective evaluation in patients used MTX/Cisplatin/5-FU/Cyclophosphamide in the oncology ward HUSM during stay in Hospital.
Result: This paper reports how the effect of cytotoxic drugs (MTX, cisplatin, 5 FU and cyclophosphamide to the patient as well as creatinine clearance relationship with creatinine clearance of urea cancer patient.
