Vivien Leigh F. Pasicolan
Objective: This study sought to determine the efficacy and tolerability of amlodipine and losartan on hypertensive patients in selected outpatient clinics in Davao City.
Methods: A descriptive study design was employed in this study. A non-randomized, purposive sampling was used in gathering the data. To establish with a degree of confidence if there exists a relationship between age, sex, weight and decrease in the systolic and diastolic blood pressure readings of respondents taking Amlodipine and Losartan, the pearson correlation was computed.
Results: Findings reveal that in both Amlodipine and Losartan, there was no significant decrease in the systolic blood pressure, but a significant decrease in the diastolic blood pressure of the respondents. Majority of the respondents have reached the goal clinic-recorded systolic blood pressure (si SBP) and diastolic blood pressure (si DBP) both for amlodipine and losartan. Age and weight has no significant implication on blood pressure readings of the two groups. Further, there was a weak correlation between sex and blood pressure readings on patients taking Losartan, while in Amlodipine, sex has no significant correlation on the diastolic blood pressure but significant in the systolic blood pressure readings.
Conclusion: It can be inferred that the antihypertensive effect of losartan is comparable with amlodipine. However, losartan has superior tolerability than amlodipine.
