Eunju Park
The purpose of this study was to evaluate the feasibility of
an advance directive (AD) at the time of starting first-line
palliative chemotherapy. We investigated the changes in
emotional distress, quality of life (QoL), and attitudes toward
anticancer treatments before and after the AD. Patients
with advanced cancer who had just started first-line
palliative chemotherapy were prospectively enrolled between
February 2014 and October 2016. We assessed the
attitude toward chemotherapy, the Hospital Anxiety and
Depression Scale (HADS), and the European Organization
for the Research and Treatment of Cancer Quality of
Life questionnaire (EORTC-QLQ) scores before conducting
the AD, and subsequently performed the AD after the
first cycle of chemotherapy.
