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Gastrointestinal Stromal Tumour of stomach –A case report | 25788

International Journal of Pharmacy Teaching & Practices

ISSN - 1986-8111

Abstract

Gastrointestinal Stromal Tumour of stomach –A case report and the Role of Imatinib

D. K. Das, Quah WJ

Introduction: Gastrointestinal Stromal tumour (GIST) is relatively an uncommon tumour, accounting for <1% of all gastrointestinal tract (GIT) tumours. Surgical resection for resectable cases remains the mainstay treatment. However, imatinib and most recently sutinib has emerged as a vital care for locally advanced, recurrent or metastatic cases.
Objective: We are reporting our case due to its rare occurrence and to address the important role of imatinib in GISTs.
Methods: Report of a rare case.
Results: A 62 years-old man was referred to surgical department with haematemesis for 2days. On examination patient was grossly anaemic with tachycardia and hypotension. Haemoglobin was 6.2gm%. Upper GI endoscopy showed a growth in the fundus of stomach with an ulcer in its canter. Biopsy of the growth reported as GIST. CT scan abdomen reported as having a mass of 3x4 cm. in the fundus of the stomach without any other abnormalities. After resuscitation patient was subjected to proximal gastrectomy followed by gastro-oesophageal anastamoses. Histopathological examination of the specimen reported as GIST of the stomach. Post operative period was uneventful and at the end of 4th year follow-up patient is disease free.
Conclusion: Haematemesis is a cardinal presentation of GIST of the stomach. Surgery alone is adequate for resectable GIST.

 
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