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Metformin exerts anti inflammatory effects on mouse colon sm | 57183

Journal of Health and Medical Research

Abstract

Metformin exerts anti inflammatory effects on mouse colon smooth muscle cells in vitro

Dana Al-Omari

Inflammatory bowel disease (IBD) is a chronic incurable condition characterized by relapsing inflammation of the gut. Intestinal smooth muscle cells (SMCs) are affected structurally and functionally during IBD due to excessive production of different inflammatory mediators. Met­formin is a widely used antidiabetic agent known to exert several anti inflammatory effects in different tissues inde­pendently from its hypoglycemic effect.

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