Lung cancer is the leading cause of cancer deaths worldwide. The main obstacles to this cancer's clinical success are limited therapy alternatives and resistance to existing medications. Several studies over the last decade have demonstrated the significance of microRNA (miRNA) driven cell cycle regulation in lung cancer growth. As a result, these tiny nucleotide compounds could be useful in lung cancer therapy. We highlighted current advances in lung cancer therapy employing cell cycle associated miRNAs in this review. By emphasizing the roles of particular cell cycle core regulators associated with miRNAs in lung cancer, we explained how these miRNAs might be investigated in early detection and therapy efforts to avoid lung cancer. More medical efforts can ensure a potential breakthrough in miRNA-based lung cancer therapy with the information provided in our review.
