Dibyajyoti Saha, Swati Paul
Metformin hydrochloride is 1, 1-dimethyl biguanide hydrochloride and is also a hypoglecaemic drug. Gliclazide, is a third generation sulphonyl urea class hypoglycaemic drug which acts via stimulating β- cells of the isleta of langerhans of pancreas to release insulin. Metformin HCL differs markedly from glicazide and do not stimulate pancreatic β- cells but improve lipid profile well in type 2 diabetes.The research pathways were aimed at carrying out recovery studies of metformin hydrochloride and glicazide in combined dosage form (tablets) using RP-HPLC Techniques.
