50 years since their revelation by Llinás and partners, dendritic spikes have been seen in different neurons in various mind areas, from the neocortex and cerebellum to the basal ganglia. Dendrites display a marvelously different yet cliché collection of spikes, in some cases well defined for subregions of the dendrite. Despite their commonness, we just have a brief look into their job as acting creatures. This article plans to review the full scope of dendritic spikes tracked down in excitatory and inhibitory neurons, look at them in vivo versus in vitro, and talk about new examinations depicting dendritic spikes in the human cortex. We center around neocortical and hippocampal neurons and present a guide to distinguish and grasp the more extensive job of dendritic spikes in the single-cell calculation.