Prostatic adenocarcinoma is rarely manifest as generalized lymphadenopathy. Generalised lymphadenopathy in prostatic adenocarcinoma has been reported as 0.4-1%. Generalised lymph adenopathy is explained based on the tumor emboli via thoracic duct. Most of the generalised lymph adenopathy occurs in the metastatic prostatic adenocarcinoma is misdiagnosed as lymphoma. Our patient initially diagnosed as lymphoma based on the clinical and radiological features. But later it was diagnosed as metastatic adenocarcinoma of prostate. This case is reported due to unfamiliar feature of prostate cancer which creates diagnostic difficulties.