Eosinophilic Gastroenteritis (EoG) is a rare benign entity of unknown etiology characterized by focal or diffuse eosinophilic infiltration in the small intestine. Klein et al. categorized EoG into three different patterns relying on the concept of the predominant location, extent, and depth of intestinal eosinophilic infiltration. Diagnosis can only be obtained by high clinical suspicion and histopathological confirmation after the excluding of common causes of GI eosinophilia. Treatment is primarily based on systemic corticosteroids, which improve symptoms and endoscopic lesions dramatically. This report highlights an interesting case of chronic diarrhea and mucosal EoG that was successfully treated with steroids.
