Agbayim WC
Nigeria
Research Article
Evaluation of Concurrent Administration of Leaf Extracts of Vernonia Amygdalina and Gongrenema Latifolium on some Liver Function Indices in Wistar Rats
Author(s): Njoku B, Chike CPR, Onyebuenyi MO and Agbayim WCNjoku B, Chike CPR, Onyebuenyi MO and Agbayim WC
The effects of concurrent administration of ethanolic leaf extracts of Vernonia amygdalina and Gongrenema latifolium on some liver function indices in normal wistar rats. Seventy (70) male wistar rats were used in the study. The animals were divided into seven (7) groups of ten rats each. Group I was given 1 ml of distilled water and served as the control. Groups II and III received 100 mg/kg and 300 mg/kg bw of Vernonia amygdalina. Groups IV and V received 300 mg/kg and 600 mg/kg bw of Gongrenema latifolium, while groups VI and VII received 100 mg/kg V. amygdalina +300 mg/kg G. latifolium, and 300 mg/kg V. amygdalina + 600 mg/kg bw Gongrenema latifolium respectively orally once daily for a period of 28 days. Five (5) animals from each group were sacrificed after days 14 and 28 respectively, and blood samples coll.. View More»
