Amro F. Alhabib
Saudi Arabia
Research Article
Effect of Magnesium Sulfate on the Total Anesthetic and Analgesic Requirements in Neurosurgery
Author(s): Essam M. Manaa and Amro F. AlhabibEssam M. Manaa and Amro F. Alhabib
Background: Anesthesia for neurosurgery requires balancing deep and effective anesthesia as well as
postoperative analgesia versus the risks of delayed recovery and postoperative respiratory depression. This
randomized, placebo-controlled, double-blind study was designed to evaluate the effect of magnesium sulfate on the
total anesthetic and analgesic consumption using the clinical parameters in addition to the bispectral index (BIS) and
neuromuscular monitoring using train-of-four (TOF).
Patients and Methods: This study included 60 adult male and female patients, ASA physical status I and II,
and undergoing neurosurgical procedures. Patients were randomly allocated into 2 equal groups. Patients in group
I (magnesium group) received magnesium sulfate (20 mg/kg) as bolus dose over 5 minutes before induction of
anesthesia, followed.. View More»
