Cabrera de León A
Spain
Research Article
Leptin, Insulin and Lipid Profiles in Obese Subjects with and without Metabolic Syndrome in the Region of Cap-Bon: Tunisia
Author(s): Gannar Fadoua, Cabrera de León A, Marzougui Ferid, Sakly Mohsen and Attia NebilGannar Fadoua, Cabrera de León A, Marzougui Ferid, Sakly Mohsen and Attia Nebil
Aims: To evaluate the effect of obesity associated or not with Metabolic Syndrome (MS) on leptinemia, insulinemia and lipid profile in subjects from the region of Cap-Bon in northeastern Tunisia. Methods: Ninety seven individuals were included in this study. Anthropometric parameters (Body Mass Index (BMI), Waist Circumference (WC) and Hip Circumference (HC), metabolic parameters (Total Cholesterol (TC), LDL-C, HDL-C, Non-Esterified Fatty Acids (NEFA), Triglycerides (TG), CËÂ?Reactive Protein (CRP), glucose) and hormones (insulin and leptin) were determined. Insulin resistance was estimated by Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). Metabolic syndrome was identified with the International Diabetes Federation (IDF) criteria. Results: Obese patients with and without MS, Ob-MS and Ob groups, have significantly increased plasma levels of glucose, TG, TC, LDL-C and decre.. View More»
