Research Article
Nonalcoholic Fatty Liver Disease (NAFLD), a Manifestation of the Metabolic Syndrome: New Perspectives on the Nutritional Therapy
Author(s): Aline de Piano, Débora Estadella, Lila M. Oyama, Eliane B Ribeiro, Ana R Dâmaso and Claudia M da Penha Oller do NascimentoAline de Piano, Débora Estadella, Lila M. Oyama, Eliane B Ribeiro, Ana R Dâmaso and Claudia M da Penha Oller do Nascimento
Nonalcoholic fatty liver disease (NAFLD) is a multifactorial hepatic disease that develops through complex
mechanisms that may be strongly influenced by dietary composition. NAFLD treatment is based on multidisciplinary
intervention, which includes nutritional aspects. The objective of this review was to elucidate the influence and role of
dietary composition, including fatty acid types, antioxidant nutrients, pre and probiotics and vitamin D in the nutritional
treatment and prevention of NAFLD. Increased intake of Monounsaturated fatty acids (MUFAs) and omega-3
polyunsaturated fatty acid (PUFA), particularly as replacements for saturated fat and in a higher proportion than
carbohydrates, is beneficial to NAFLD patients, improving insulin resistance; increasing plasma levels of adiponectin
and its synthesis by the adipose tissue; and restoring the expression of hepatic peroxisome .. View More»
