Cynthia D Santos
Tanzania
Research Article
The Impact of the Drug Overdose Epidemic on the Mortality of Persons
with HIV/AIDS
Author(s): Alex F Manini and Cynthia D SantosAlex F Manini and Cynthia D Santos
Introduction: In the highly active anti-retroviral therapy (HAART) era, acquired immunodeficiency syndrome (AIDS)-related causes of death have declined, while non-AIDS-related causes, especially drug overdose and liver disease, have become a leading cause of death in persons with human immunodeficiency virus (HIV). Excess mortality among HIV-infected patients has been identified in those with substance use dependence. Our aim was to review the recent literature regarding the impact of HIV/AIDS on the current drug overdose epidemic with respect to the HAART era (1997 onwards).
Methods: This systematic review screened Pubmed database using search terms (HIV, AIDS, HAART, overdose, hepatitis, nephropathy, opioid, acetaminophen, methadone) and included cohort studies with derived mortality rates while excluding indiv.. View More»
