Elif G Umit
Edirne
Turkey
Research Article
Multiple Myeloma and Thromboembolism in the Perspective of Age and Performance
Author(s): Elif G Umit, Mehmet Baysal and Muzaffer Demir AElif G Umit, Mehmet Baysal and Muzaffer Demir A
Introduction: The relation with cancer and thromboembolism (TE) are well documented. Within cancer types, hematological malignancies, especially Multiple Myeloma (MM) show a propensity towards TE with its disease biology, disease burden and treatments. We aimed to evaluate the risk factors of TE and MM with a perspective of age and clinical performance. Methods: Data regarding Eastern Cooperative Oncology Group (ECOG) and Karnofsky performance scores, patient, disease and treatment related properties of patients with MM between 2010 and 2016 were recorded. Results: Of the 125 MM patients, 60 were female (48%) while 65 were male (52%). Median age was 65 years. TE was observed in 28 patients (22.4%). In patients <65 years, poor ECOG and Karnofsky scores were strongly related with TE (p values 0.003 and 0.000). Polypharmacy and LDH elevation were observed to be risk factors in all age.. View More»
