Esraa Mamdouh Yousef
Egypt
Research Article
Anti-HB Core Screening Significance among Healthy Blood Donors in Fayoum, Egypt
Author(s): Hossam M. Abdelaziz, Sohair Fahmy, Amel Soliman and Esraa Mamdouh YousefHossam M. Abdelaziz, Sohair Fahmy, Amel Soliman and Esraa Mamdouh Yousef
Background: Occult Hepatitis B is the existence of HBV-DNA in the serum of HBsAg negative cases with or without the presence of antibodies to HBV. Although (HBV)transmission viahepatitisB surface antigen (HBsAg) negative blood donors has beenreported, still HBsAg is the only obligatory HBV screening test of blood donors in Fayoum.
Aim: Expanding the donor screening procedure to include anti-HBc to reduce the risk of transfusion transmitted HBV infection.
Methods: A total of 400 HBsAg negative blood donors were included in the study from blood bank, Fayoum University Hospital, Egypt. All donors were tested for anti-HBc, and HBsAg-negative, anti-HBc-positive sera were further tested quantitatively for antibodies to hepatitis B surface antigen (anti-HBs). ‘Anti-HBc alone’ sera were examined quantitatively for HBV by real t.. View More»
