Frederick T. Murphy
Tanzania
Case Report
Iron Study is a Weak Indicator in Symptomatic C282Y/ H63D Compound Heterozygotes
Author(s): Wael Toama, Almaan El-Attrache, Neel Patel and Frederick T. MurphyWael Toama, Almaan El-Attrache, Neel Patel and Frederick T. Murphy
Hemochromatosis is a metabolic disease with protean manifestations including polyarthritis. It is often under diagnosed due to poor classification criteria, ambiguity in laboratory testing and the inability to obtain a histological diagnosis. The current DNA testing for hemochromatosis may not adequately identify patients at risk for indolent chronic migratory arthropathy secondary to this condition. In this case, we present a patient with compound heterozygotes of hemochromatosis laboratory testing, indolent chronic migratory polyarthritis, generalized weakness, depression and abnormal iron studies. Our subject presented to medical attention with a four-year history of indolent chronic migratory polyarthritis resulting in multiple orthopedic surgeries including right shoulder replacement and left ankle fusion. The patient?s laboratory results including Complete Blood Count (CBC) and .. View More»
