Fujio T
Japan
Research Article
Predictors Affecting Left Ventricular Geometry in Non-Hypertensive,Healthy Subjects: Association of Concentric Remodelling With EarlyDiastolic Dysfunction
Author(s): Ken S, Yuri O, Haruki S, Yufuko T, Fujio T and Masatoshi KKen S, Yuri O, Haruki S, Yufuko T, Fujio T and Masatoshi K
Abstract The geometric patterns of remodelling are related to hemodynamic and traditional cardiovascular risk factors; however, the clinical significance of left ventricular (LV) concentric remodelling (CR) with a normal LV mass and small LV cavity in a general population is not known well. This study assessed the prevalence, predictors and function of LV CR in healthy subjects without hypertension. For cross-sectional analysis, 1049 subjects were enrolled and examined using conventional and tissue Doppler echocardiography. Parameters measured included diastolic function (septal e’, E/e’), LV mass index (LVMI) and relative wall thickness (RWT). All subjects were categorized into four LV geometric patterns by LVMI and RWT (Normal geometry (N), normal LVMI and RWT; CR, normal LVMI and high RWT; concentric hypertrophy (CH), increased LVMI and high RWT; eccentric hypertrophy (.. View More»