Guilherme Perassa Gasque
Department of Neurology, Pedro Ernesto University Hospital, State University of Rio de Janeiro (UERJ), Rio de Janeiro, RJ,
Brazil
Case Report
Paraneoplastic and Idiopathic Ganglionopathy: Importance of Differential
Diagnosis
Author(s): Guilherme Perassa Gasque, Felipe da Rocha Schmidt, Diogo Matheus Terrana de Carvalho, Salim Balassiano, Jose Marcelo Ferreira Bezerra and Marcia Rodrigues JardimGuilherme Perassa Gasque, Felipe da Rocha Schmidt, Diogo Matheus Terrana de Carvalho, Salim Balassiano, Jose Marcelo Ferreira Bezerra and Marcia Rodrigues Jardim
Sensory ganglionopathies (SG) may occur in association with different diseases and are characterized by the degeneration of the primary sensory neurons located in the dorsal root ganglia. The most important associated conditions are paraneoplastic SG, HIV infection, Sjogren's syndrome, and cisplatin or pyridoxine toxicity. Even when clinical criteria help differentiate SG from other neuropathies, an etiological diagnosis remains elusive. Thus, there is a need to identify biological markers than can distinguish immune-mediated SG from other etiologies. Objectives: The present study of two cases of SG compares their neurological outcomes with their treatment responses in accordance with the etiology of each one. Methods: evaluate the clinical presentation and examination results to be able to define the etiology and institute early treatment. Results: To dif.. View More»
