Hafiza Sobia Ramzan
Institute of Molecular Biology and Biotechnology,
Lahore
Pakistan
Research Article
Radiotherapy is One of the Effective and Common Measures of Pancreatic Cancer Therapy: Iodine-125 (125i) Brachytherapy Improves Local Control and Increase Survival
Author(s): Hafiza Sobia Ramzan, Hafiz Faizan Lateef and Qamar ZamanHafiza Sobia Ramzan, Hafiz Faizan Lateef and Qamar Zaman
Introduction: The malignant tumors of torment and life taking pancreatic cancer account for adeno-carcinoma which finds its origin in the exocrine secretions of pancreas. Though a lot many techniques and methodologies are surfacing in the field of medical science but still the overall survival rate is not remarkable. The recommended treatment for local tumor control is the implantation of the I125 radioactive seed (brachytherapy) in the effected organ.
Objective: This study was carried out in order to reveal the individual and synergistic efficacy of I125 and ING4 for the treatment of pancreatic cancer tumors. Both in vitro (pancreatic cell lines) and in vivo (in mouse model) investigations were performed.
Material and methods: The vibrant combination of ING4 and radiotherapy with I125.. View More»
