Heidrun Gehlen
Germany
Research Article
Investigation of a Putative Novel Papillomavirus that causes InvertedPapillomas in Horses
Author(s): Antonia Ertelt, Olivia Kershaw, Christine Förster, Matthias König and Heidrun GehlenAntonia Ertelt, Olivia Kershaw, Christine Förster, Matthias König and Heidrun Gehlen
The Papillomaviridae family comprises a large number of viruses that can infect a broad range of hosts giving rise to benign lesions of the skin or mucosal membranes. Until today, seven viruses termed EcPV1-7 were identified in equine papillomas.
Two trotter stallion siblings at the age of two were referred to the Equine Clinic of Free University of Berlin, because of erythema, alopecia and crusting. After a diagnosis of immune-mediated skin disease, the horses underwent long-term treatment with glucocorticoids and azathioprine. Two months later, both horses developed hundreds of small wart-like proliferations on the head, neck, chest and trunk. Six healthy horses, housed in the same stable, were used to assess the occurrence of the virus in healthy skin.
Biopsies were obtained for histopathology and for amplification and cloning of the papillomavirus genome as wel.. View More»
