Hiroshi Okamoto
Minami-Otsuka Institute of Technology, Minami-Otsuka Clinic,
2-41-9 Minami-Otsuka, Toshima-ku, Tokyo, 170-0005
Japan
Research Article
Causes of Death in Autopsied Patients with Rheumatoid Arthritis in Japan
Author(s): Mariko Kitahama, Hiroshi Okamoto, Chihiro Terai, Yumi Koseki, Tadashi Sakurai and Naoyuki KamataniMariko Kitahama, Hiroshi Okamoto, Chihiro Terai, Yumi Koseki, Tadashi Sakurai and Naoyuki Kamatani
Objective: To investigate causes of death in Japanese patients with Rheumatoid Arthritis (RA) and whether recent RA treatment has been associated with a decrease in AA-amyloidosis among RA patients.
Methods: Data from records of RA patients autopsied in Japan during 2000-2004 and 1985-1989 were analyzed. Cause of death, age at death, gender, and incidence of amyloidosis were assessed.
Results: The average age at death in the recent RA group was 69.1 years in 817 females and 70.1 years in 408 males. Unlike the general population, RA females died earlier than males. In the past 15 years, a survival rate of RA patients has improved. The leading cause of death of recently diagnosed RA patients was infection (32.8%), respiratory diseases (20.2%), and AA-amyloidosis (11.3%). In comparison with patients surveyed in 1985-1.. View More»
