Hossein Omidian
College of Pharmacy,
3200 South University Drive, Fort Lauderdale, FL, 33314
Tanzania
Review Article
Drug Tampering and Abuse Deterrence
Author(s): Hossein Omidian and David J MastropietroHossein Omidian and David J Mastropietro
There has been a growing response from governments, industries, and academic institutions to address the worldwide incidence of prescription drug abuse. These organizations have addressed this prominent public health concern in different ways. One crucial step has been research and development into developing medications that are considerably more resistant to abuse. These novel medications prevent or discourage abuse and tampering, and consequently referred to most often as abuse-deterrent or tamper-resistant formulations. While prescription drugs used to treat insomnia, anxiety, and behavioral disorders are commonly abused, prescription opioids are most significant. Attempts to produce more rapid “high” or euphoria have resulted in various tampering techniques by abusers. Swallowing multiple dosage forms at once, either intact or crushed (chewed), is relatively considere.. View More»