Jorge Alejandro Mateos-Parra
Mexico
Case Report
Levamisole Induced Autoimmunity
Author(s): Nina Tello, Jorge Alejandro Mateos-Parra and Alejandro Díaz-BorjónNina Tello, Jorge Alejandro Mateos-Parra and Alejandro Díaz-Borjón
Abstract Background: We present the case of a patient with vitiligo that was treated with levamisol and presented with pure levamisole induced vasculopathy. The patient had no cocaine use and immunologic findings persisted for more than 4 years after the consumption of the drug. Case Presentation: 70 year-old women with a history relevant for vitiligo. Shortly after initiating levamisole she developed extensive necrotic skin lesions, coagulopathy and thrombocytopenia. At the time she presented an hemorragic stroke that resulted in hemiparesia. Four months later, she presented with loss of consciousness and a mixed aphasia. A CT scan revealed the prior lesion only, an EEG showed abnormal activity. Her lab tests showed a positive lupus anticoagulant and p-ANCA. She was initially managed with phenytoin, levetiracetam and enoxaparin. She returned with a status epilepticus and was then man.. View More»
