Khaled M Alsubiaee
College of Medicine, King Saud bin Abdulaziz University for Health Sciences,
P.O. Box 5193 Riyadh 1142
Saudi Arabia
Research Article
The Effects of Vitamin D Supplementation in Patients with Knee Osteoarthritis: Uncontrolled Open Label Clinical Trial
Author(s): Khaled M Alsubiaee, Khalid T Alkhathlan, Amir Omair and Farhan M AleneziKhaled M Alsubiaee, Khalid T Alkhathlan, Amir Omair and Farhan M Alenezi
Background: Osteoarthritis (OA) is a degenerative disease that affects joints. The current relationship between low vitamin D levels, functions, and symptoms of osteoarthritis is controversial. Objective: The aim of this study is to investigate the relationship between knee osteoarthritis and serum levels of vitamin D.
Method: An uncontrolled open label clinical trial conducted on patients with low vitamin D levels using the Western Ontario and McMaster Universities Arthritis Index (WOMAC criteria). The WOMAC criteria used objectively to assess knee-joint function and symptoms before and after vitamin D3 supplementation. The study conducted from March 2013 to October 2015 at King Abdulaziz Medical City. Riyadh, Saudi Arabia. All participants with knee osteoarthritis and low vitamin D levels (≤75 nmol/L) were given 45,000 IU of vitamin D3 .. View More»
