Kobkan Thongprasom
Faculty of Dentistry,
Bangkok
Thailand
Case Report
Carcinoma In situ arising in the Oral Lichenoid Lesion-An Unusual Case Report
Author(s): Ekarat Phattarataratip, Kittipong Dhanuthai and Kobkan ThongprasomEkarat Phattarataratip, Kittipong Dhanuthai and Kobkan Thongprasom
Drug-induced lichenoid reaction is quite common in the oral cavity. Patients with oral lichenoid lesions (OLL) may increase risk of developing epithelial dysplasia and squamous cell carcinoma. Although this subject remains controversial, several studies suggested that the overall rate of malignant transformation of OLL was greater than that of general population or patients with oral lichen planus (OLP). In the present article, we report a 66-year-old female Thai patient with OLL associated with many medications including simvastatin. She also had a history of hypertension, osteoarthritis and hepatitis B virus infection. Her physician treated her with amlodipine, etoricoxib, glucosamine and chondroitin sulfate for more than 20 years. Simvastatin had been prescribed for the treatment of dyslipidemia for 2 years. Notably, the patient reported that oral symptoms and lesions arose after t.. View More»
