Review Article
P300 Evoked Potential and Risk of Mild Cognitive Impairment
Progression to Alzheimers Dementia: A Literature Review
Author(s): Marco Túlio Gualberto Cintra, Moacir Cesar Silva Tavares, Sérgio Augusto Gomes, Thiago de Oliveira Gonçalves, Luciana Cristina Matos da Cunha, Denise Utsch Gonçalves, Edgar Nunes de Moraes and Maria Aparecida Camargos BicalhoMarco Túlio Gualberto Cintra, Moacir Cesar Silva Tavares, Sérgio Augusto Gomes, Thiago de Oliveira Gonçalves, Luciana Cristina Matos da Cunha, Denise Utsch Gonçalves, Edgar Nunes de Moraes and Maria Aparecida Camargos Bicalho
Introduction: Great efforts have been made to develop diagnostic methods for precisely screen patients with mild cognitive impairment (MCI) who will progress to dementia. Many biomarkers have been studied for that. However, their high costs, small availability and need for invasive procedures sometimes make these biomarkers of limited usefulness. With the advantages of its low cost and being non-invasive, the P300 evoked potential (EP) is one methods under investigation.
Objective: To assess whether the P300 evoked potential can estimate the risk of MCI progression to Alzheimer’s dementia (AD).
Methods: Review of the PubMed database using the descriptors: “evoked potentials”, “Alzheimer’s disease” and “mild cognitive impairment”.
Results: We selected eight among 929 articles after applying the exclusion criteria. .. View More»
