Masamitsu Nakazato
Japan
Research Article
High-Frequency Oscillation and Recovery Functions of Somatosensory Evoked Potentials in Human T-Cell Lymphotropic Virus Type 1- Associated Myelopathy
Author(s): Nobuyuki Ishii, Hitoshi Mochizuki, Kazutaka Shiomi and Masamitsu NakazatoNobuyuki Ishii, Hitoshi Mochizuki, Kazutaka Shiomi and Masamitsu Nakazato
Objectives: Human T-cell lymphotropic virus type 1–associated myelopathy (HAM) involves not only spinal cord but also the cerebral cortex and the white matter in histopathological analysis. In addition, a previous study found that T2 hyperintensities on brain magnetic resonance imaging (MRI) in HAM patients were increased only in white matter. However, conventional neurophysiological examination of somatosensory pathway did not identify any abnormalities in the cerebral cortex or white matter. We evaluated the inhibitory function of the cerebral sensory cortex in HAM patients by analyzing high-frequency oscillations (HFOs) and somatosensory evoked potential recovery functions (SEP-Rs). Method: Eight HAM patients were enrolled in the present investigation. Twenty age-matched healthy subjects were enrolled (10 for HFOs, 10 for SEP-Rs). SEP was recorded from the hand sensory area c.. View More»
