Michael Geffard
France
Research Article
Noradrenaline-Immunoreactive Neuronal Structures in the Cat Dorsal
Vagal Complex: Interaction with Pargyline, Parachlorophenylalanine or
Colchicine Pretreatment
Author(s): Keiko Ikemoto, Michael Geffard, Yves Tillet and Kunio KitahamaKeiko Ikemoto, Michael Geffard, Yves Tillet and Kunio Kitahama
We examined the localization and chemical nature of neurons immunoreactive to noradrenaline (NA) in the cat’s dorsal vagal complex (DVC), using immunohistochemistry for NA, dopamine-β-hydroxylase (DBH), dopamine (DA) and tyrosine hydroxylase, under different conditions. In non-treated animals, localization of NA-immunoreactive (-ir) and DBH-ir neurons extensively overlapped. They were found mainly in the caudal portion of the nucleus of the solitary tract (NTS), and a small number in the dorsal motor nucleus of the vagus. Most were restricted to the commissural and ventral sub nuclei of the NTS. In the area postrema, we observed a small number of weakly stained NA-ir cell bodies alongside numerous intensely stained DBH-ir ones. Injection of the monoamine oxidase inhibitor (MAOI), pargyline, enhanced NA immunoreactivity in cells and axons of the DVC and increased their numbe.. View More»
