Michiya Igase
Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon City, Ehime 791-0295,
Japan
Research Article
Prevalence and Associated Clinical Factors of GERD (Gastro-Esophageal Reflux Disease) in Ischemic Stroke Patients
Author(s): Michiya Igase, Katsuhiko Kohara, Keiji Igase, Shiro Yamashita, Mutsuo Fujisawa, Ryosuke Katagi and Tetsuro MikiMichiya Igase, Katsuhiko Kohara, Keiji Igase, Shiro Yamashita, Mutsuo Fujisawa, Ryosuke Katagi and Tetsuro Miki
Purpose: Aspirin is protective against ischemic stroke, but its use is a significant risk factor for gastro-esophageal reflux disease (GERD). We investigated the prevalence and associated clinical factors of GERD in ischemic stroke patients treated with aspirin.
Methods: We recruited 116 ischemic stroke outpatients who were receiving aspirin. Sixteen patients who had received proton pump inhibitors or H2 receptor antagonists within the previous month were excluded. The presence of GERD was defined using the GerdQ questionnaire, with a score of 8 or higher considered positive for GERD. Logistic regression analysis was conducted using variables which exhibited a significant correlation coefficient on two-group comparison as factors, with the presence or absence of GERD as the dependent variable.
Results: Mean age of the 100 patients analyzed was 69.3 ± 8.9 years. Th.. View More»
