Rafał Rola
Military Institute of Aviation Medicine, Neurologia,
Poland
Research Article
Optimizing Final Electrode Placement Based on Intraoperative Neurophysiological Evaluation during Subthalamic Deep Brain Stimulation for Parkinson's Disease
Author(s): Rafał Rola, Marcin Tutaj, Henryk Koziara, Dariusz Koziorowski, Bogdan Brodacki, Michał Karliński, Tomasz Tykocki, Bartosz Krolicki and Tomasz MandatRafał Rola, Marcin Tutaj, Henryk Koziara, Dariusz Koziorowski, Bogdan Brodacki, Michał Karliński, Tomasz Tykocki, Bartosz Krolicki and Tomasz Mandat
Background and purpose: Target point identification based solely on MRI and CT of subthalamic nucleus (STN) in deep brain stimulation procedures (DBS) for Parkinson’s disease (PD) might have suboptimal clinical effects. The authors analyse alterations of permanent electrode location depending on neurophysiological evaluation compared to an anatomically based calculated target.
Materials and methods: The group comprised 66 patients (32 females and 34 males) aged 57.6 (38–76) years, in whom 131 electrodes were implanted. The patients were qualified for the surgery according to the CAPSIT-PD criteria. STN was identified using the direct and indirect methods, based on 1.5 T MRI and CT. The surgery was performed under local anesthesia. Two to 5 microelectrodes were used for microrecording and macrostimulation.
Results: Anterior (49.2%), central (35.6%) and lateral (13.6%) traj.. View More»
