Ragab A Mahfouz
Zagazig University Hospital,
Egypt
Research Article
Impact Of The Neutrophil-to-Lymphocyte Ratio On Coronary Flow Reserve And Incipient Myocardial Dysfunction In Patients With Psoriatic Arthritis
Author(s): Ragab A Mahfouz, Tamer Mostafa and Dalia S FahmyRagab A Mahfouz, Tamer Mostafa and Dalia S Fahmy
Aim: The aim of the present study was to investigate the impact of Neutrophil-Lymphocyte Ratio (NLR) on Coronary Flow Reserve (CFR) and incipient myocardial dysfunction in patients with Psoriatic Arthritis (PsA) without risk for coronary artery disease.
Methods and results: We analyzed clinical, hematologic, echocardiographic and CFR data of 68 patients (mean age 41.5 ± 8.2years), who had no risk factor for coronary artery disease. Sixty-two healthy subjects were served as control group. NLR was significantly higher in patients with PsA versus control subjects (7.86 ± 0.6 vs. 1.39 ± 0.6, P<0 .0001). CFR was significantly lower in patients with PsA than in control subjects (1.9 ± 0.3 vs. 3.6 ± 0.2; P <0.002). The myocardial function was significantly impaired in patients than control subjects (E/E&rsqu.. View More»
