Roman Jirák
Czech Republic
Research Article
Correlation of Depression, Behavioral Disorders and Delirium with Certain Genetic Abnormalities in Patients with Alzheimer’s Disease
Author(s): Ada Manukyan, Roman Jirák, Jiří Raboch, Zdeněk Fišar, Martina Zvěřová and Pavel MartásekAda Manukyan, Roman Jirák, Jiří Raboch, Zdeněk Fišar, Martina Zvěřová and Pavel Martásek
Objectives: The aim of this study was to find out how some of the genetic polymorphisms influence the clinical picture of the dementia syndrome, in other words how some clinical features correlate with certain genetic abnormalities.
Methods: Altogether 183 people were examined; they were either ambulatory patients of the Psychiatric clinic or people of corresponding age. Patients that suffered with Alzheimer’s disease numbered 86, healthy control subjects numbered 97. A single blood sample was collected from each of the test subjects in order to be used for genetic testing.
Results: The statistical analysis of the data about the influence of individual polymorphisms on the development of depression, behavioral disorders and delirium at the group of patients with Alzheimer’s disease was made. The acquire.. View More»
