Rosa Lippolis
Institute of Biomembranes and Bioenergetics (IBBE), National Research Council (CNR),
70124 Bari
Italy
Review Article
Proteomics and Human Diseases
Author(s): Rosa Lippolis and Maria De AngelisRosa Lippolis and Maria De Angelis
Proteomics, the large scale study of proteins and protein variations, contributes to a better understanding of the molecular basis of variability in susceptibility to diseases that are associated with genetic diversity and environmental factors. The development of proteomic technologies has permitted the unprecedented large-scale identification of proteins in any biological system. Human proteomics point out physiological conditions that could greatly impact on medicine. This knowledge has the potential to decode the pathogenic mechanisms underlying diseases, elucidate potential risk factors and molecular targets for drug development and therapeutic interventions and identify promising biomolecules that could be developed for diagnostic and prognostic purposes and for improved disease management strategies. Thus proteomics can translate basic scientific discoveries into the clinical p.. View More»
DOI: 10.4172/jpb.1000391
