Salem Abdelhady
Cairo
Egypt
Research Article
Axonal Neuropathy in Multiple Sclerosis Patients Treated with Interferon ?
Author(s): Salem Abdelhady and Hebatallah RashedSalem Abdelhady and Hebatallah Rashed
Introduction: Peripheral neuropathy has been reported as a rare side effect of interferon α (INF α) but not with interferon β (IFN β) treatment.
Objectives: In the current study we aimed at studying the risk of occurrence of neuropathy as well as its pattern in a group of multiple sclerosis (MS) patients receiving IFN β.
Methods: We studied the clinical manifestations and electrophysiological pattern of peripheral neuropathy in two groups of multiple sclerosis (MS) patients group I involved 12 patients receiving interferon β and group II involved 28 patients receiving cytotoxic medications.
Results: We revealed electrophysiological abnormalities of nerve conduction suggesting axonal sensory-motor neuropathy in 7 patients (58.3%) out of 12 receiving INF β in co.. View More»