Samina Hyder Haq
Science College,
Riyadh
Saudi Arabia
Commentary
DNA Methylation Pattern and their Effect on Ageing
Author(s): Samina Hyder HaqSamina Hyder Haq
DNA methylation is one of the epigenetic modifications which have been implicated in cellular differentiation, aging, and diseases progression. In this commentary, we discussed the significant role of methylation pattern and imprinting in the cellular differentiation in light of the earlier published work. This is an attempt to highlight the importance of methylation factors in health and disease and explore the potential of various nutritional therapeutic agents directly affecting the methylation pattern of DNA. The role of external dietary chemical and environmental factors contributing towards the epigenetic imprinting has been suggested, but the exact molecular mechanisms through which these dietary and environmental agents mediate their action on genomic methylation pattern require future investigation. One of the possible mechanisms which warrant future investigation is to explo.. View More»
