Schrenzel J
Switzerland
Research Article
Microbiologic and Inflammatory Markers of Periodontitis are Different to those of Preterm Birth
Author(s): Lumbreras Areta M, Gayet-Ageron A, Roux-Lombard P, Schrenzel J, Baehni P, Irion O and Martinez de Tejada BLumbreras Areta M, Gayet-Ageron A, Roux-Lombard P, Schrenzel J, Baehni P, Irion O and Martinez de Tejada B
Background: Comparing microbiologic and inflammatory markers of periodontitis with those of preterm birth (PTB).
Methods: Secondary analysis of a prior prospective case-control study done at the Geneva University Hospitals. Cases were women delivering at 22-34 6/7 weeks (early PTB, n=30) and controls were women delivering at ≥ 37 weeks (term delivery, n=87). We collected dental plaque during labour to quantify RNA levels from Aggregatibacter actinomycetemcomitans (Aa), Tannerella forsythia (Tf), Porphyromonas gingivalis (Pg) and Treponema denticola (Td). We also collected cord blood for cultures and cytokine quantification (IL-1Ra, IL-6, IL-8, IL-10, IL-17, TNF-α, MCP-1 and RANTES). Periodontal status was evaluated at the immediate postpartum using the American Consensus definition. Data was analysed by univariate .. View More»
