Seung Chan Kim
Medical School and College of Medicine, Department of Integrated OMICS for Biomedical Sciences (World Class University Program), The School of Graduate Studies, Yonsei University, Yonsei-ro 50, Shinchon-dong, Seodaemoon-gu, Seoul,
Republic of Korea
Research Article
Low Intensity (0.2T) Static Magnetic Field for Dispersing Nucleus Ankyrin
G in Human Cultured Glioblastoma Cells
Author(s): Seung Chan Kim, Wooseok Im and Beom Jin KimSeung Chan Kim, Wooseok Im and Beom Jin Kim
Biomagnetism is one of important biotechnology fields for manipulation of cell lines. However, its peri-cellular level regulation, upon stimulation is not fully developed. Glioblastoma U87 and U251 represent a malignant model in rapid growing cancer. We focused in cellular level dispersion of static magnetic fields (0.2T=2000 ± 600 Gauss), using its fast growing properties. As a result, cytoskeletal protein nuclear Ankyrin G was dispersed. Membrane barriers in TEM microscopy indicated the membranous apparatus change. Our findings bring an insight that static magnetic stimulation creates a specified cytoplasmic intracellular pattern.. View More»
