Smyrnova Ganna
Department of Internal Medicine №1, Donetsk M.Gorky National Medical University,
Ukraine
Research Article
Hematological Abnormalities in Ukrainian Patients with Rheumatoid Arthritis
Author(s): Vatutin Mykola, Smyrnova Ganna and Taradin GennadiyVatutin Mykola, Smyrnova Ganna and Taradin Gennadiy
Objective: This study aims to investigate hematological abnormalities in Ukrainian patients with rheumatoid arthritis (RA) and analyze their causes.
Patients and methods: Eighty nine patients who met the American College of Rheumatology (ACR) criteria for RA were included in this study. Individuals with no history of joint pains were enrolled as healthy controls, and matched for age and ethnicity with patients of RA. All patients received methotrexate (10.5 ± 5.5 mg/week) in combination with folic acid. Steroid hormones were prescribed to 92% (19.3 ± 3.8 mg/day) of patients; nonsteroidal anti-inflammatory drugs were taken on demand. The blood count was measured to determine the white blood cell (WBC), red blood cell (RBC), hemoglobin and thrombocyte levels. TNFα, CRP and IL-1β were also investigated.
.. View More»
