Soheir M Zalabani
Egypt
Research Article
Anti-inflammatory and Antimicrobial Activity of the Different Conyza dioscoridis L. Desf. Organs
Author(s): Soheir M Zalabani, Mona H Hetta and Ahmed S IsmailSoheir M Zalabani, Mona H Hetta and Ahmed S Ismail
Objectives: This study was planned in order to assess the anti-inflammatory and antimicrobial potential of the different organs (leaf, flower and root) of Conyza dioscoridis (L.) Desf.
Methods: A preliminary phytochemical and chromatographic screening of the ethanol (70%) extracts was performed prior investigation. Successive extraction of the plant organs was carried out with petroleum ether 60-80°C, chloroform, ethyl acetate and ethanol 90%, and percentage yield of extractives was determined. The anti-inflammatory activity of the total ethanol (70%) extracts was evaluated in-vivo by the carrageenan-induced rat paw oedema method, as compared to Indomethacin. The antimicrobial activity of the total ethanol and successive extracts was assessed by the agar dilution method on a set of bacteria and fungi; MICs were determin.. View More»