Tomasz Mandat
Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Warszawa,
Poland
Research Article
Pallidal or Subthalamic Deep Brain Stimulation for the Generalized Dystonia Treatment
Author(s): Tomasz Mandat, Krzysztof Szalecki, Henryk Koziara, Emilia Soltan, Bartosz Krolicki, Bartosz Czapski, Bogdan Brodacki, Wieslaw Bonicki and Tomasz KmiecTomasz Mandat, Krzysztof Szalecki, Henryk Koziara, Emilia Soltan, Bartosz Krolicki, Bartosz Czapski, Bogdan Brodacki, Wieslaw Bonicki and Tomasz Kmiec
One of the most effective treatments of medically refractory generalized dystonia (GD) is pallidal deep brain stimulation (GPi DBS). For selected group of GD patients’ subthalamic deep brain stimulation (STN DBS) might be similarly effective. The authors present a group of patients diagnosed with GD, treated with GPi or STN DBS.
Materials and methods: Between 2005 and 2009 eleven female and eight male patients with diagnosed GD were treated with GPi DBS or STN DBS. Mean age at implantation was 26 ± 6. Two patients were diagnosed with DYT-1 mutation. Seven patients were diagnosed with PANK-2 mutation. One patient with previous bilateral pallidotomies and six patients with diagnosed PANK-2 mutation were qualified to STN DBS. Rest of the group was qualified to GPi DBS. Clinical status of the patients was evaluated with a package of dystonia scales. Th.. View More»
