Tsuneaki Yoshinaga
Department of Neurology and Rheumatology, Shinshu University Hospital, 3-1-1 Asahi Matsumoto 390-8621,
Japan
Case Report
A Case Report of WEBINO Syndrome with Convergence Impairment
Author(s): Tsuneaki Yoshinaga, Katsuya Nakamura, Kazuma Kaneko and Akinori NakamuraTsuneaki Yoshinaga, Katsuya Nakamura, Kazuma Kaneko and Akinori Nakamura
A 73-year-old man suddenly presented with alternating exotropia, bilateral medial longitudinal fasciculus (MLF)
syndrome, and impaired convergence. This symptom has been known as wall-eyed bilateral internuclear
ophthalmoplegia (WEBINO syndrome). Diffusion-weighted images on magnetic resonance imaging showed a smalllocalized
lesion in his pontine tegmentum. Based on he had some ischemic risk factors; he was diagnosed as having
an ischemic stroke and started an antiplatelet therapy. His convergence impairment was improved, but abduction
impairment of the right eye remained even 3 months later.
The causing lesion of WEBINO syndrome has been reported to be either midbrain or pons mainly due to ischemic
strokes or demyelinating diseases. In some cases, this syndrome was accompanied by convergence impairment;
however, the pathophysiol.. View More»
